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A higher incidence of noso comial fungal infection in winter,e lderly patients,and those with resp iratory disease was obvious. 冬季、老年、原发病为呼吸系统疾病者发病率较高;广谱抗生素、免疫抑制剂、皮质类固醇的大量应用及各种导管技术的开展是主要易感因素。